DelveInsight’s “Sarcopenia Pipeline Insight 2026” report provides comprehensive insights about 18+ companies and 20+ pipeline drugs in the Sarcopenia pipeline landscape. It covers the Sarcopenia pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Sarcopenia therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

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Key Takeaways from the Sarcopenia Pipeline Report

• On June 09, 2026- Seoul National University Hospital initiated a clinical trial evaluates whether postoperative administration of branched chain amino acids affects skeletal muscle mass index and sarcopenia related functional outcomes in patients undergoing total knee arthroplasty.
• In May 2026- Sengkang General Hospital conducted a study is performed in Singapore (outside the US) and the medication, while it is a FDA approved medication, is not manufactured in the US for the trial purpose and the indications of use in this trial is not new.
• In May 2026- Pluto Inc. announced a Phase 2 study is designed to evaluate the efficacy and safety of PLH-2301 in subjects with sarcopenia. Approximately 168 eligible subjects will be randomized in a 1:1:1:1 ratio to receive placebo or PLH-2301 at dose levels of 200 mg, 400 mg, or 600 mg administered orally once daily for 12 weeks.
• DelveInsight’s Sarcopenia pipeline report depicts a robust space with 18+ active players working to develop 20+ pipeline therapies for Sarcopenia treatment.
• The leading Sarcopenia Companies such as Biophytis, Epirium Bio, Turn Biotechnologies, Immunis, Oncocross, BPGbio, Inc. and others.
• Promising Sarcopenia Pipeline Therapies such as AMC6156 0.1mg, Bimagrumab, MK-0773, REGN1033 (SAR391786), LPCN 1148, BIO101, Olimel N12, Glucose IV, Testosterone Enanthate, Finasteride, and others.

Stay informed about the cutting-edge advancements in Sarcopenia treatments @ Sarcopenia Clinical Trials Assessment

The Sarcopenia Pipeline Report provides disease overview, pipeline scenario and therapeutic assessment of the key pipeline therapies in this domain. The Sarcopenia Pipeline Report also highlights the unmet needs with respect to the Sarcopenia.

Sarcopenia Overview

Sarcopenia is a progressive, age-related condition characterized by the loss of skeletal muscle mass, strength, and function. It primarily affects older adults and is associated with an increased risk of falls, frailty, reduced mobility, and overall decline in quality of life. While aging is the primary driver, other contributing factors include chronic diseases, inflammation, hormonal changes, poor nutrition, and physical inactivity. Sarcopenia is now recognized as a distinct disease by the World Health Organization (WHO) and is increasingly gaining attention in clinical research due to its significant impact on aging populations.

Sarcopenia Emerging Drugs Profile

• BIO101: Biophytis

Sarconeos (BIO101) is a small molecule proto-oncogene protein c-mas-1 agonist that is administered orally. Based on results from cellular and animal studies, it is believed that Sarconeos (BIO101) stimulates biological resilience through activation of the MAS receptor and may have the potential to improve muscle function and preserve strength, mobility, and respiratory capacity in various age-related and muscular wasting conditions. The drug showed a very good safety profile at the doses of 175 mg bid and of 350 mg bid with no Serious Adverse Events (AE) related to the product in the Phase II clinical trial study. The drug is currently in Phase II stage of clinical trial evaluation for the treatment of Sarcopenia.

• MF-300: Epirium Bio

MF-300 is an orally bioavailable small molecule that reversibly binds to the Prostaglandin E2 (PGE2)-binding site of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), an enzyme that converts PGE2 to an inactive metabolite. MF-300 target engagement inhibits 15-PGDH activity, stabilizing and increasing levels of PGE2 in a cell-based assay and in vivo in skeletal muscle in preclinical studies.

In humans and rodents, 15-PGDH gene expression is elevated in muscle coincident with the onset of age-induced muscle weakness. PGE2, a lipid signaling molecule with multiple beneficial effects on the motor unit, including enhanced muscle quality and improved function of the neuromuscular junction, is reduced in skeletal muscle of aged mice due to increased activity of 15-PGDH. Inhibiting 15-PGDH in aged muscle may be a strategy to increase physiologic levels of PGE2 to improve muscle quality and function. Currently, the drug is in the Phase I stage of its development for the treatment of Sacropenia.

• TRN005: Turn Biotechnologies

TRN-005 is a unique formulation to restore muscle mass and strength, and reverse age-related conditions that compromise people’s ability to lead active lifestyles. Preclinical results demonstrated improvement in stem cell growth and differentiation, acceleration of muscle recovery, increases in fiber thickness and force output. The drug is currently in Preclinical stage of development for the treatment of Sarcopenia.

Learn more about Sarcopenia Drugs opportunities in our groundbreaking Sarcopenia research and development projects @ Sarcopenia Unmet Needs

The Sarcopenia Pipeline Report provides insights into

• The report provides detailed insights about companies that are developing therapies for the treatment of Sarcopenia with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Sarcopenia Treatment.
• Sarcopenia Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Sarcopenia Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Sarcopenia market.

Sarcopenia Companies

Biophytis, Epirium Bio, Turn Biotechnologies, Immunis, Oncocross, BPGbio, Inc. and others.

Sarcopenia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Sarcopenia Products have been categorized under various ROAs such as

• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical

Sarcopenia Products have been categorized under various Molecule types such as

• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy

Discover the latest advancements in Sarcopenia treatment by visiting our website @ Sarcopenia Market Drivers and Barriers, and Future Perspectives

Scope of the Sarcopenia Pipeline Report

• Coverage- Global
• Sarcopenia Companies- Biophytis, Epirium Bio, Turn Biotechnologies, Immunis, Oncocross, BPGbio, Inc. and others.
• Sarcopenia Pipeline Therapies- AMC6156 0.1mg, Bimagrumab, MK-0773, REGN1033 (SAR391786), LPCN 1148, BIO101, Olimel N12, Glucose IV, Testosterone Enanthate, Finasteride, and others.
• Sarcopenia Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Sarcopenia Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Read the full details of Sarcopenia Pipeline on our website @ Sarcopenia Emerging Drugs and Companies

Table of Contents

1. Introduction
2. Executive Summary
3. Sarcopenia Overview
4. Sarcopenia Pipeline Therapeutics
5. Sarcopenia Therapeutic Assessment
6. Sarcopenia – DelveInsight’s Analytical Perspective
7. Mid Stage Sarcopenia Products (Phase II)
8. BIO101: Biophytis
9. Early Stage Sarcopenia Products (Phase I)
10. MF-300: Epirium Bio
11. Preclinical Stage Products
12. TRN005: Turn Biotechnologies
13. Inactive Sarcopenia Products
14. Sarcopenia Companies
15. Sarcopenia Key Products
16. Sarcopenia Unmet Needs
17. Sarcopenia Market Drivers and Barriers
18. Sarcopenia- Future Perspectives and Conclusion
19. Sarcopenia Analyst Views
20. Appendix

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